JOHN DUFRESNE se otè sis woman: Louisiana Power & Light: A Novel ak Love Warps the Mind a Little: A Novel (toude te pami Liv Remakab pou Ane a selon New York Times); Deep in the Shade of Paradise: A Novel; Requiem, Mass.: A Novel; No Regrets, Coyote: A Novel; ak I Don't Like Where This Is Going: A Wylie Coyote Novel. Li te ekri tou de koleksyon istwa kout: The Way That Water Enters Stone: Stories ak Johnny Too Bad: Stories, ansanm ak twa ti liv: Lethe, Cupid, Time and Love; Well Enough Alone: Two Stories and Thirteen Poems; ak I Will Eat a Piece of the Roof and You Can Eat the Window. Li se otè de liv tou sou ekriti ak kreyativite: The Lie That Tells a Truth: a Guide to Writing Fiction ak Is Life Like This?: a Guide to Writing Your First Novel in Six Months. Li te ekri yon pyès teyat konplè, Trailerville, ki te jwe nan Blue Heron Theatre nan Nouyòk an 2005, ak senaryo pou kout fim The Freezer Jesus ki te ranpòte prim. Li te ko-ekri tou senaryo pou fim "To Live and Die in Dixie" a avèk Don Papy. Li te yon bousye Guggenheim pou ane 2012-2013 epi li anseye nan pwogram MFA nan Florida International University nan Miami.